BDBM381391 4-chloro-N-(4-isopropylphenyl)-1- (tetrahydro-2H-thiopyran-4-yl)-1H- pyrazolo[3,4-b]pyridine-5- carboxamide::US10272074, Example 224

SMILES CC(C)c1ccc(NC(=O)c2cnc3n(ncc3c2Cl)C2CCSCC2)cc1

InChI Key InChIKey=XNRBGHWMAUNLJQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 381391   

TargetGlucocorticoid receptor(Homo sapiens (Human))
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM381391(4-chloro-N-(4-isopropylphenyl)-1- (tetrahydro-2H-t...)
Affinity DataIC50: <50nMAssay Description:The assay was performed using H4 neuroglioma cells and using indirect immunofluorescence detection of the endogenous GR receptor. Fixative: 4% PFA. P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent