BDBM381442 4-chloro-1-((1-isopropyl-1H- imidazol-2-yl)methyl)-3-methyl-N- (4-(trifluoromethyl)phenyl)-1H- pyrazolo[3,4-b]pyridine-5- carboxamide::US10272074, Example 275
SMILES CC(C)n1ccnc1Cn1nc(C)c2c(Cl)c(cnc12)C(=O)Nc1ccc(cc1)C(F)(F)F
InChI Key InChIKey=AFOKWFWHJRGJMX-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 381442
TargetGlucocorticoid receptor(Homo sapiens (Human))
Sanford Burnham Prebys Medical Discovery Institute
US Patent
Sanford Burnham Prebys Medical Discovery Institute
US Patent
Affinity DataIC50: <50nMAssay Description:The assay was performed using H4 neuroglioma cells and using indirect immunofluorescence detection of the endogenous GR receptor. Fixative: 4% PFA. P...More data for this Ligand-Target Pair