BDBM38204 US10093650, Example 8::US10329273, Example 8::US11479538, Example 8

SMILES Fc1cc(OCCCC(F)(F)F)ccc1[C@@]1(CC(c2ccn(n2)C2CCC2)=C(C(=O)N1)n1nn[nH]c1=O)C(F)(F)F

InChI Key InChIKey=VCNFALDAFCYLKN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 38204   

TargetAlpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM38204(US10093650, Example 8 | US10329273, Example 8 | US...)
Affinity DataIC50:  30nMpH: 7.4Assay Description:The MGAT enzyme reactions were performed in Corning FALCONŽ 96-well polypropylene plates, in a total volume of 60 μL of 50 mM potassium phosphat...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target2-acylglycerol O-acyltransferase 2(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM38204(US10093650, Example 8 | US10329273, Example 8 | US...)
Affinity DataIC50:  30nMAssay Description:The MGAT enzyme reactions were performed in Corning FALCONŽ 96-well polypropylene plates, in a total volume of 60 μL of 50 mM potassium phosphat...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAlpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM38204(US10093650, Example 8 | US10329273, Example 8 | US...)
Affinity DataIC50:  30nMAssay Description:The MGAT enzyme reactions were performed in Corning FALCONŽ 96-well polypropylene plates, in a total volume of 60 μL of 50 mM potassium phosphat...More data for this Ligand-Target Pair
In DepthDetails US Patent