BDBM382217 US10273244, Example 64::US10584135, Example 64

SMILES Cn1c(SCCCN2C[C@@H]3CCN([C@@H]3C2)c2ccc(F)cc2)nnc1C1CCCCC1

InChI Key InChIKey=XUKSGYGUDPUQCB-SIKLNZKXSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 382217   

TargetD(3) dopamine receptor(Homo sapiens (Human))
Indivior

US Patent
LigandPNGBDBM382217(US10273244, Example 64 | US10584135, Example 64)
Affinity DataKi:  0.182nMAssay Description:[3H]-Spiperone Binding Assay at hD3 and hD4 recombinant receptors CHO cells transiently transfected with human dopamine type 3 or 4 receptors (CHO-hD...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(3) dopamine receptor(Homo sapiens (Human))
Indivior

US Patent
LigandPNGBDBM382217(US10273244, Example 64 | US10584135, Example 64)
Affinity DataKi:  0.182nMAssay Description:3H]-Spiperone Binding Assay at hD3 and hD4 recombinant receptors CHO cells transiently transfected with human dopamine type 3 or 4 receptors (CHO-hD3...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(2) dopamine receptor(Homo sapiens (Human))
Indivior

US Patent
LigandPNGBDBM382217(US10273244, Example 64 | US10584135, Example 64)
Affinity DataKi:  43.7nMAssay Description:CHO cells stably expressing human dopamine receptor type 2, long variant (hD2L), coupled to Gα16 protein (CHO-Gα16-hD2L) were seeded into b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(2) dopamine receptor(Homo sapiens (Human))
Indivior

US Patent
LigandPNGBDBM382217(US10273244, Example 64 | US10584135, Example 64)
Affinity DataKi:  43.7nMAssay Description:Functional Calcium Assay at hD2 recombinant receptor. CHO cells stably expressing human dopamine receptor type 2, long variant (hD2L), coupled to G&#...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent