BDBM383178 US10278962, Compound 13

SMILES CC(O)(COC(=O)c1ccc(cc1)C#N)[C@@H]1C[C@H](OC(=O)c2ccc(cc2)C#N)[C@@]2(C)Oc3cc(oc(=O)c3C(=O)[C@@H]2C1)-c1cccnc1

InChI Key InChIKey=WEOCJMZXRUXKAV-NSZDKMDOSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 383178   

TargetSterol O-acyltransferase 2(Homo sapiens (Human))
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences

US Patent
LigandPNGBDBM383178(US10278962, Compound 13)
Affinity DataIC50:  23nMAssay Description:1. Purpose:The analogues of Pyripyropene A structure were tested for their inhibitory effect on ACAT2 activity at intact cellular level by a method i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSterol O-acyltransferase 2(Homo sapiens (Human))
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences

US Patent
LigandPNGBDBM383178(US10278962, Compound 13)
Affinity DataIC50:  12nMAssay Description:1. Purpose:The analogues of Pyripyropene A structure were tested for their inhibitory effect on ACAT2 activity at intact cellular level by a method i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSterol O-acyltransferase 1(Homo sapiens (Human))
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences

US Patent
LigandPNGBDBM383178(US10278962, Compound 13)
Affinity DataIC50:  1.78E+4nMAssay Description:1. Purpose:The analogues of Pyripyropene A structure were tested for their inhibitory effect on ACAT2 activity at intact cellular level by a method i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent