BDBM383557 US10280149, Example 66::[1-(3,3-difluorocyclobutyl)-3-piperidyl]-(6-methoxy-2-naphthyl)methanone

SMILES COc1ccc2cc(ccc2c1)C(=O)C1CCCN(C1)C1CC(F)(F)C1

InChI Key InChIKey=JRYMSOZKLGEFQC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 383557   

TargetLysine-specific demethylase 2B(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM383557(US10280149, Example 66 | [1-(3,3-difluorocyclobuty...)
Affinity DataIC50:  67.5nMAssay Description:Full length KDM2B was cloned, expressed, and purified to homogeneity. Compound inhibition of KDM2B demethylase activity was assessed by monitoring th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent