BDBM383563 6-(1-cyclobutylpiperidine-3-carbonyl)-1-methyl-2-naphthonitrile::US10280149, Example 72

SMILES Cc1c(ccc2cc(ccc12)C(=O)C1CCCN(C1)C1CCC1)C#N

InChI Key InChIKey=XMZLYKSIQWSTJK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 383563   

TargetLysine-specific demethylase 2B(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM383563(6-(1-cyclobutylpiperidine-3-carbonyl)-1-methyl-2-n...)
Affinity DataIC50:  87.5nMAssay Description:Full length KDM2B was cloned, expressed, and purified to homogeneity. Compound inhibition of KDM2B demethylase activity was assessed by monitoring th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent