BDBM383625 US10280149, Example 137b

SMILES COc1ccc2cc(ccc2c1)C(=O)[C@@H]1CN(CC2CC2)CC[C@H]1C

InChI Key InChIKey=HZUBEOCLOUFFLQ-QVKFZJNVSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 383625   

TargetLysine-specific demethylase 2B(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM383625(US10280149, Example 137b)
Affinity DataIC50:  92.8nMAssay Description:Full length KDM2B was cloned, expressed, and purified to homogeneity. Compound inhibition of KDM2B demethylase activity was assessed by monitoring th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent