BDBM383668 6-(1-cyclobutyl-4-methylpiperidine-3-carbonyl)-2-naphthonitrile::US10280149, Example 161b

SMILES C[C@@H]1CCN(C[C@H]1C(=O)c1ccc2cc(ccc2c1)C#N)C1CCC1

InChI Key InChIKey=SSHMIFUCSXMGPO-QVKFZJNVSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 383668   

TargetLysine-specific demethylase 2B(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM383668(6-(1-cyclobutyl-4-methylpiperidine-3-carbonyl)-2-n...)
Affinity DataIC50:  12.3nMAssay Description:Full length KDM2B was cloned, expressed, and purified to homogeneity. Compound inhibition of KDM2B demethylase activity was assessed by monitoring th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent