BDBM383679 (1-cyclobutylpiperidin-3-yl)(6-(methylsulfonyl)naphthalen-2-yl)methanone::US10280149, Example 170

SMILES CS(=O)(=O)c1ccc2cc(ccc2c1)C(=O)C1CCCN(C1)C1CCC1

InChI Key InChIKey=ZDQZASMQTOZRRP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 383679   

TargetLysine-specific demethylase 2B(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM383679((1-cyclobutylpiperidin-3-yl)(6-(methylsulfonyl)nap...)
Affinity DataIC50:  42.6nMAssay Description:Full length KDM2B was cloned, expressed, and purified to homogeneity. Compound inhibition of KDM2B demethylase activity was assessed by monitoring th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent