BDBM383691 2-(2-methoxy-6-(4-methyl-1-propylpiperidine-3-carbonyl)naphthalen-1-yl)acetonitrile::US10280149, Example 181b

SMILES CCCN1CC[C@H](C)[C@@H](C1)C(=O)c1ccc2c(CC#N)c(OC)ccc2c1

InChI Key InChIKey=FNVOUZJJWZBGSV-HRAATJIYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 383691   

TargetLysine-specific demethylase 2B(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM383691(2-(2-methoxy-6-(4-methyl-1-propylpiperidine-3-carb...)
Affinity DataIC50:  12.3nMAssay Description:Full length KDM2B was cloned, expressed, and purified to homogeneity. Compound inhibition of KDM2B demethylase activity was assessed by monitoring th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent