BDBM383695 US10280149, Example 183b

SMILES CC[C@H]1CCN(C[C@@H]1C(=O)c1ccc2c(CC#N)c(OC)ccc2c1)C1CCC1

InChI Key InChIKey=IVYXIZSSLAKIFL-SBUREZEXSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 383695   

TargetLysine-specific demethylase 2B(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM383695(US10280149, Example 183b)
Affinity DataIC50:  2.06nMAssay Description:Full length KDM2B was cloned, expressed, and purified to homogeneity. Compound inhibition of KDM2B demethylase activity was assessed by monitoring th...More data for this Ligand-Target Pair
In DepthDetails US Patent