BDBM384125 (1-(3-(3,5-dichloro- phenyl)-1H- pyrazolo[3,4-b]- pyrazin-6-yl)-4- methylpiperidin-4-yl) methanamine::US10280171, Example 11::US10851110, Example 11::US11466017, Example 11
SMILES CC1(CN)CCN(CC1)c1cnc2c(n[nH]c2n1)-c1cc(Cl)cc(Cl)c1
InChI Key InChIKey=RQJVSHGOYHHYSM-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 384125
TargetTyrosine-protein phosphatase non-receptor type 11 [E76K](Homo sapiens (Human))
Board of Regents, The University of Texas System
US Patent
Board of Regents, The University of Texas System
US Patent
Affinity DataIC50: 632nMAssay Description:Phosphatase activity of full length wild-type PTPN11(PTPN11-WT) or PTPN11-E76K mutant enzyme was measured using the fluorogenic 6,8-difluoro-4-methyl...More data for this Ligand-Target Pair