BDBM384274 US10280184, Example F.1.40

SMILES CN1CCn2nc(Nc3cc(cn4ncnc34)[C@@H]3CCCN(C3)C(=O)C=C)cc2C1

InChI Key InChIKey=FPYSHWCKTAUZER-OAHLLOKOSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 384274   

TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM384274(US10280184, Example F.1.40)
Affinity DataIC50: <100nMAssay Description:The in-house BTK corresponds to recombinant human catalytic domain (aa 393-659), which was expressed in SF9 cells with an N-terminal his tag and puri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent