BDBM384991 2-(dimethylamino)-N-{(1S)-2- hydroxy-2-methyl-1-[4- (pentafluoro-lambda6- sulfanyl)phenyl]propyl}-6-oxo- 1,6-dihydropyrimidine-4- carboxamide::US10285989, Example 211

SMILES CN(C)c1nc(cc(=O)[nH]1)C(=O)N[C@@H](c1ccc(cc1)S(F)(F)(F)(F)F)C(C)(C)O

InChI Key

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 384991   

TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM384991(2-(dimethylamino)-N-{(1S)-2- hydroxy-2-methyl-1-[4...)
Affinity DataKi:  0.0730nMAssay Description:The activity of the compounds in accordance with the present invention as PDE2 inhibitors may be readily determined using a fluorescence polarization...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent