BDBM385209 US10287267, Compound 433::US10508099, Compound 433::US10556885, Compound 433::US11174244, Compound 433::US11673881, Compound 433

SMILES Cn1cc(nn1)-c1ccc2cnc(NC(=O)C3CC3)cc2c1

InChI Key InChIKey=LETZRMJUBWQCKB-UHFFFAOYSA-N

Data  12 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 385209   

TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Biosplice Therapeutics

US Patent
LigandPNGBDBM385209(US10287267, Compound 433 | US10508099, Compound 43...)
Affinity DataEC50:  1.90nMAssay Description:The DYRK1A kinase assay was run using the Ser/Thr 18 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologies??a Divi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Biosplice Therapeutics

US Patent
LigandPNGBDBM385209(US10287267, Compound 433 | US10508099, Compound 43...)
Affinity DataEC50:  1nMAssay Description:The GSK3β kinase assay is run using the Ser/Thr 09 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologies??a D...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent