BDBM385389 (3 S)-1-[5-[(E)-2-(Aminomethyl)-3-fluoro-allyloxy]pyrimidin-2-yl]pyrrolidin-3-ol; Dihydrochloride::US10287270, Example 6::US10464928, Example 6::US10793552, Example 6

SMILES NC\C(COc1cnc(nc1)N1CC[C@H](O)C1)=C/F

InChI Key InChIKey=PGWHLRYXOSBDBE-RZCNENHTSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 385389   

TargetMembrane primary amine oxidase(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM385389((3 S)-1-[5-[(E)-2-(Aminomethyl)-3-fluoro-allyloxy]...)
Affinity DataIC50:  52nMAssay Description:Amine oxidase activity of recombinant SSAO, MAOa, and MAOb isoforms are measured using the MAO-Glo™ assay kit from Promega (V1402). Test compounds (w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMembrane primary amine oxidase(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM385389((3 S)-1-[5-[(E)-2-(Aminomethyl)-3-fluoro-allyloxy]...)
Affinity DataIC50:  52nMAssay Description:Amine oxidase activity of recombinant SSAO, MAOa, and MAOb isoforms are measured using the MAO-Glo™ assay kit from Promega (V1402). Test compounds (w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMembrane primary amine oxidase(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM385389((3 S)-1-[5-[(E)-2-(Aminomethyl)-3-fluoro-allyloxy]...)
Affinity DataIC50:  52nMAssay Description:Amine oxidase activity of recombinant SSAO, MAOa, and MAOb isoforms are measured using the MAO-Glo™ assay kit from Promega (V1402). Test compounds (w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent