BDBM385674 4-[5- (dimethylamino)- [1,2,4]triazolo[1,5- a]pyrimidin-7- yl]benzonitrile::US10287286, Example 82

SMILES CN(C)c1cc(-c2ccc(cc2)C#N)n2ncnc2n1

InChI Key InChIKey=HPAGEUKPYIALBE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 385674   

TargetProlyl hydroxylase EGLN2(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM385674(4-[5- (dimethylamino)- [1,2,4]triazolo[1,5- a]pyri...)
Affinity DataIC50:  11nMAssay Description:The IC50 values for the PHD1 enzyme (residues 1-407) were determined by mixing increasing amounts of a compound of the invention with a fixed amount ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent