BDBM389976 4-[1-(4-Chlorophenyl)-1H- pyrrolo[2,3-c]pyridin-2- yl]pyridin-2-amine::US10766897, Compound 147::US10968223, Compound 147::US9951068, Compound 147

SMILES Nc1cc(ccn1)-c1cc2ccncc2n1-c1ccc(Cl)cc1

InChI Key InChIKey=PQODUJCHPMUWBZ-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 389976   

TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Proximagen

US Patent
LigandPNGBDBM389976(4-[1-(4-Chlorophenyl)-1H- pyrrolo[2,3-c]pyridin-2-...)
Affinity DataIC50:  5.50E+3nMAssay Description:Electrophysiological recordings were made from a Chinese Hamster Lung cell line stably expressing the full length hERG channel. Single cell ion curre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMembrane primary amine oxidase(Homo sapiens (Human))
Proximagen

US Patent
LigandPNGBDBM389976(4-[1-(4-Chlorophenyl)-1H- pyrrolo[2,3-c]pyridin-2-...)
Affinity DataIC50: <50nMAssay Description:SSAO: All primary assays were performed at RT. with purified recombinantly expressed human SSAO. Enzyme was prepared essentially as described in Öhma...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Proximagen

US Patent
LigandPNGBDBM389976(4-[1-(4-Chlorophenyl)-1H- pyrrolo[2,3-c]pyridin-2-...)
Affinity DataIC50:  5.50E+3nMAssay Description:Compounds of the invention were tested for inhibition of the human ether a go-go related gene (hERG) K+ channel using IonWorks patch clamp electrophy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMembrane primary amine oxidase(Homo sapiens (Human))
Proximagen

US Patent
LigandPNGBDBM389976(4-[1-(4-Chlorophenyl)-1H- pyrrolo[2,3-c]pyridin-2-...)
Affinity DataIC50: <50nMAssay Description:All primary assays were performed at RT. with purified recombinantly expressed human SSAO. Enzyme was prepared essentially as described in Öhman et a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMembrane primary amine oxidase(Homo sapiens (Human))
Proximagen

US Patent
LigandPNGBDBM389976(4-[1-(4-Chlorophenyl)-1H- pyrrolo[2,3-c]pyridin-2-...)
Affinity DataIC50: <50nMAssay Description:SSAO: All primary assays were performed at RT. with purified recombinantly expressed human SSAO. Enzyme was prepared essentially as described in Öhma...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Proximagen

US Patent
LigandPNGBDBM389976(4-[1-(4-Chlorophenyl)-1H- pyrrolo[2,3-c]pyridin-2-...)
Affinity DataIC50:  5.50E+3nMAssay Description:hERG: Compounds of the invention were tested for inhibition of the human ether a go-go related gene (hERG) K+ channel using IonWorks patch clamp elec...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMembrane primary amine oxidase(Homo sapiens (Human))
Proximagen

US Patent
LigandPNGBDBM389976(4-[1-(4-Chlorophenyl)-1H- pyrrolo[2,3-c]pyridin-2-...)
Affinity DataIC50: <50nMAssay Description:All primary assays were performed at RT. with purified recombinantly expressed human SSAO. Enzyme was prepared essentially as described in Öhman et a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent