BDBM390984 (2S,5S)-tert-butyl 5- (cyanomethyl)-5-(3-((2- methyl-1,1-dioxido-2,3- dihydrobenzo[d]isothiazol- 5-yl)amino)-4-oxo-4,5- dihydro-1H-pyrazolo[4,3- c]pyridin-1-yl)tetrahydro- 2H-pyran-2-carboxylate (from I-14-1A)::US9957264, Example 5-55
SMILES CN1Cc2cc(Nc3nn(c4cc[nH]c(=O)c34)[C@]3(CC#N)CC[C@H](OC3)C(=O)OC(C)(C)C)ccc2S1(=O)=O
InChI Key
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 390984
Affinity DataIC50: 0.120nMAssay Description:The ability of compounds to inhibit the activity of JAK1, JAK2, JAK3, and Tyk2 was measured using a recombinant purified GST-tagged catalytic domain ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0500nMAssay Description:The ability of compounds to inhibit the activity of JAK1, JAK2, JAK3, and Tyk2 was measured using a recombinant purified GST-tagged catalytic domain ...More data for this Ligand-Target Pair