BDBM391024 (2S,5S)-tert-butyl 5- (cyanomethyl)-5-(4- oxo-3-((1-oxo-2-(2,2,2- trifluoroethyl)isoindolin-5- yl)amino)-4,5-dihydro-1H- pyrazolo[4,3-c]pyridin-1- yl)tetrahydro-2H-pyran-2- carboxylate (from I-14-1A)::US9957264, Example 5-95
SMILES CC(C)(C)OC(=O)[C@@H]1CC[C@](CC#N)(CO1)n1nc(Nc2ccc3C(=O)N(CC(F)(F)F)Cc3c2)c2c1cc[nH]c2=O
InChI Key
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 391024
Affinity DataIC50: 0.200nMAssay Description:The ability of compounds to inhibit the activity of JAK1, JAK2, JAK3, and Tyk2 was measured using a recombinant purified GST-tagged catalytic domain ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0700nMAssay Description:The ability of compounds to inhibit the activity of JAK1, JAK2, JAK3, and Tyk2 was measured using a recombinant purified GST-tagged catalytic domain ...More data for this Ligand-Target Pair