BDBM391025 (2S,5S)-tert-butyl 5-(3-((4- ((1H-1,2,3-triazol-1- yl)methyl)phenyl)amino)- 4-oxo-4,5-dihydro-1H- pyrazolo[4,3-c]pyridin-1- yl)-5-(cyanomethyl) tetrahydro-2H-pyran-2- carboxylate (from I-14-1A)::US9957264, Example 5-96
SMILES CC(C)(C)OC(=O)[C@@H]1CC[C@](CC#N)(CO1)n1nc(Nc2ccc(Cn3ccnn3)cc2)c2c1cc[nH]c2=O
InChI Key
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 391025
Affinity DataIC50: 0.340nMAssay Description:The ability of compounds to inhibit the activity of JAK1, JAK2, JAK3, and Tyk2 was measured using a recombinant purified GST-tagged catalytic domain ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0700nMAssay Description:The ability of compounds to inhibit the activity of JAK1, JAK2, JAK3, and Tyk2 was measured using a recombinant purified GST-tagged catalytic domain ...More data for this Ligand-Target Pair