BDBM391107 US9957264, Example 5-178::[(3S)-3-{3-[(2-tert-butyl- 1,1-dioxido-2,3-dihydro- 1,2-benzisothiazol-5-yl) amino]-4-oxo-4,5-dihydro- 1H-pyrazolo[4,3-c] pyridin-1-yl}tetrahydro- 2H-pyran-3-yl] acetonitrile (from I-17B)
SMILES CC(C)(C)N1Cc2cc(Nc3nn(c4cc[nH]c(=O)c34)[C@]3(CC#N)CCCOC3)ccc2S1(=O)=O
InChI Key
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 391107
Affinity DataIC50: 0.170nMAssay Description:The ability of compounds to inhibit the activity of JAK1, JAK2, JAK3, and Tyk2 was measured using a recombinant purified GST-tagged catalytic domain ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0400nMAssay Description:The ability of compounds to inhibit the activity of JAK1, JAK2, JAK3, and Tyk2 was measured using a recombinant purified GST-tagged catalytic domain ...More data for this Ligand-Target Pair