BDBM391187 2-((3R,4R or 3S,4S)-3- fluoro-4-(3-((3-methyl-4- (morpholine-4- carbonyl)phenyl)amino)-4- oxo-4,5-dihydro-1H- pyrazolo[4,3-c]pyridin-1- yl)tetrahydro-2H-pyran-4- yl)acetonitrile (derived from I-22A)::US9957264, Example 5-258
SMILES Cc1cc(Nc2nn(c3cc[nH]c(=O)c23)[C@]2(CC#N)CCOC[C@@H]2F)ccc1C(=O)N1CCOCC1
InChI Key
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 391187
Affinity DataIC50: 0.0800nMAssay Description:The ability of compounds to inhibit the activity of JAK1, JAK2, JAK3, and Tyk2 was measured using a recombinant purified GST-tagged catalytic domain ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0700nMAssay Description:The ability of compounds to inhibit the activity of JAK1, JAK2, JAK3, and Tyk2 was measured using a recombinant purified GST-tagged catalytic domain ...More data for this Ligand-Target Pair