BDBM391201 2-((3R,4R or 3S,4S)-4-(3- ((1,1-dioxido-2-(piperidin-4- yl)-2,3-dihydrobenzo [d]isothiazol-5- yl)amino)-4-oxo-4,5- dihydro-1H-pyrazolo[4,3- c]pyridin-1-yl)-3- fluorotetrahydro-2H-pyran- 4-yl)acetonitrile (from I- 22A)::US9957264, Example 5-272
SMILES F[C@H]1COCC[C@@]1(CC#N)n1nc(Nc2ccc3c(CN(C4CCNCC4)S3(=O)=O)c2)c2c1cc[nH]c2=O
InChI Key
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 391201
Affinity DataIC50: 0.100nMAssay Description:The ability of compounds to inhibit the activity of JAK1, JAK2, JAK3, and Tyk2 was measured using a recombinant purified GST-tagged catalytic domain ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0600nMAssay Description:The ability of compounds to inhibit the activity of JAK1, JAK2, JAK3, and Tyk2 was measured using a recombinant purified GST-tagged catalytic domain ...More data for this Ligand-Target Pair