BDBM391366 US9957264, Example 21-2::[(1R,2R)-1-{3-[(3,3- dimethyl-2-oxo-2,3- dihydro-1H-indol-6- yl)amino]-4-oxo-4,5- dihydro-1H-pyrazolo[4,3- c]pyridin-1-yl}-2- fluorocyclohexyl] acetonitrile (from I-19A)
SMILES CC1(C)C(=O)Nc2cc(Nc3nn(c4cc[nH]c(=O)c34)[C@@]3(CC#N)CCCC[C@H]3F)ccc12
InChI Key
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 391366
Affinity DataIC50: 0.0400nMAssay Description:The ability of compounds to inhibit the activity of JAK1, JAK2, JAK3, and Tyk2 was measured using a recombinant purified GST-tagged catalytic domain ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0400nMAssay Description:The ability of compounds to inhibit the activity of JAK1, JAK2, JAK3, and Tyk2 was measured using a recombinant purified GST-tagged catalytic domain ...More data for this Ligand-Target Pair