BDBM39188 4,4-Dimethyl-3H,4H-5,11-dioxa-2,3-diaza-cyclopenta[c]phenanthren-10-one::MLS000028242::SMR000012236::cid_646236

SMILES CC1(C)Oc2ccc3ccc(=O)oc3c2-c2cn[nH]c12

InChI Key InChIKey=JIWOOKVVUNWVMP-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 39188   

TargetRho-associated protein kinase 2(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM39188(4,4-Dimethyl-3H,4H-5,11-dioxa-2,3-diaza-cyclopenta...)
Affinity DataIC50:  267nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetDNA dC->dU-editing enzyme APOBEC-3A(Homo sapiens (Human))
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM39188(4,4-Dimethyl-3H,4H-5,11-dioxa-2,3-diaza-cyclopenta...)
Affinity DataIC50:  4.45E+3nMT: 2°CAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetDNA dC->dU-editing enzyme APOBEC-3G(Homo sapiens (Human))
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM39188(4,4-Dimethyl-3H,4H-5,11-dioxa-2,3-diaza-cyclopenta...)
Affinity DataIC50:  5.70E+3nMT: 2°CAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM39188(4,4-Dimethyl-3H,4H-5,11-dioxa-2,3-diaza-cyclopenta...)
Affinity DataIC50: >3.10E+4nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute, TSRI Assay Provide...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay