BDBM39236 2-amino-6-(1,3-benzodioxol-5-yl)-4,4-dimethoxy-3-azabicyclo[3.1.0]hex-2-ene-1,5-dicarbonitrile::4-amino-6-(1,3-benzodioxol-5-yl)-2,2-dimethoxy-3-azabicyclo[3.1.0]hex-3-ene-1,5-dicarbonitrile::4-azanyl-6-(1,3-benzodioxol-5-yl)-2,2-dimethoxy-3-azabicyclo[3.1.0]hex-3-ene-1,5-dicarbonitrile::MLS000085495::SMR000020430::cid_3237447

SMILES COC1(OC)N=C(N)C2(C#N)C(c3ccc4OCOc4c3)C12C#N

InChI Key InChIKey=PNKPXOCANVHXSM-UHFFFAOYSA-N

Data  2 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 39236   

TargetRho-associated protein kinase 2(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM39236(2-amino-6-(1,3-benzodioxol-5-yl)-4,4-dimethoxy-3-a...)
Affinity DataIC50:  4.80E+4nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...More data for this Ligand-Target Pair
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TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM39236(2-amino-6-(1,3-benzodioxol-5-yl)-4,4-dimethoxy-3-a...)
Affinity DataIC50: >9.31E+4nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute, TSRI Assay Provide...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetSerine/threonine-protein kinase 33(Homo sapiens (Human))
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM39236(2-amino-6-(1,3-benzodioxol-5-yl)-4,4-dimethoxy-3-a...)
Affinity DataEC50: >1.20E+5nMAssay Description:Keywords: STK33 Kinase, Non-ATP Competitive Inhibitor Assay Overview: Purified STK33 Kinase is preincubated with potential inhibitors and allowed to ...More data for this Ligand-Target Pair
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TargetZinc finger protein mex-5(Caenorhabditis elegans)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM39236(2-amino-6-(1,3-benzodioxol-5-yl)-4,4-dimethoxy-3-a...)
Affinity DataEC50:  6.43E+4nMAssay Description:Broad Institute: MLPCN maternal gene expression Project ID: 2024 Keywords: Zinc finger, C. elegans, maternal gene expression, RNA-protein interac...More data for this Ligand-Target Pair
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TargetPOsterior Segregation(Caenorhabditis elegans)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM39236(2-amino-6-(1,3-benzodioxol-5-yl)-4,4-dimethoxy-3-a...)
Affinity DataEC50:  5.99E+4nMAssay Description:Broad Institute: MLPCN maternal gene expression Project ID: 2024 Keywords: Zinc finger, C. elegans, maternal gene expression, RNA-protein interac...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay