BDBM393389 3-((4'-Methoxy-5-phenoxy-[1,1'-biphenyl]-2-yl)methoxy)azetidine-1-carbonitrile::US9963444, Example 90

SMILES COc1ccc(cc1)-c1cc(Oc2ccccc2)ccc1COC1CN(C1)C#N

InChI Key InChIKey=IQWAOZKOMILBHW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 393389   

TargetN-acylethanolamine-hydrolyzing acid amidase(Homo sapiens (Human))
Northeastern University

Curated by ChEMBL
LigandPNGBDBM393389(3-((4'-Methoxy-5-phenoxy-[1,1'-biphenyl]-2-yl)meth...)
Affinity DataIC50:  5.70nMAssay Description:Inhibition of activated human NAAA using fluorogenic PAMCA and N-4-methylcoumarin as substrate incubated for 90 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetN-acylethanolamine-hydrolyzing acid amidase(Homo sapiens (Human))
Northeastern University

Curated by ChEMBL
LigandPNGBDBM393389(3-((4'-Methoxy-5-phenoxy-[1,1'-biphenyl]-2-yl)meth...)
Affinity DataIC50:  55nMAssay Description:In order to have an assay method more conducive to high-throughput screening than those published for measuring the NAE hydrolyzing activity of NAAA,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent