BDBM395638 (R)-1-((7-cyano- 2-(3'-(5-(N- isopropyl-N- methylglycyl)- 5,6-dihydro-4H- pyrrolo[3,4-d]- oxazol-2-yl)-2,2'- dimethyl-[1,1'- biphenyl]-3-yl)- benzo[d]oxazol- 5-yl)methyl)-3- methylpyrrolidine- 3-carboxylic acid::US10308644, Example 248::US10800768, Example 248::US11339149, Example 248

SMILES CC(C)N(C)CC(=O)N1Cc2nc(oc2C1)-c1cccc(c1C)-c1cccc(-c2nc3cc(CN4CC[C@](C)(C4)C(O)=O)cc(C#N)c3o2)c1C

InChI Key InChIKey=NLSGLOAWDCCCFL-RRHRGVEJSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 395638   

TargetProgrammed cell death 1 ligand 1 [19-238]/protein 1 [25-167](Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM395638((R)-1-((7-cyano- 2-(3'-(5-(N- isopropyl-N- methylg...)
Affinity DataIC50: <10nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProgrammed cell death 1 ligand 1 [19-238]/protein 1 [25-167](Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM395638((R)-1-((7-cyano- 2-(3'-(5-(N- isopropyl-N- methylg...)
Affinity DataIC50: <10nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProgrammed cell death 1 ligand 1 [19-238]/protein 1 [25-167](Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM395638((R)-1-((7-cyano- 2-(3'-(5-(N- isopropyl-N- methylg...)
Affinity DataIC50:  3.00E+3nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent