BDBM395644 (R)-1-((7-cyano- 2-(2,2'-dimethyl- 3'-(5-(2-(4- methylpiperazin- 1-yl)acetyl)-5,6- dihydro-4H- pyrrolo[3,4-d]- oxazol-2-yl)-[1,1'- biphenyl]-3-yl)- benzo[d]oxazol- 5-yl)methyl)-3-::US10308644, Example 254::US10800768, Example 254::US11339149, Example 254

SMILES CN1CCN(CC(=O)N2Cc3nc(oc3C2)-c2cccc(c2C)-c2cccc(-c3nc4cc(CN5CC[C@](C)(C5)C(O)=O)cc(C#N)c4o3)c2C)CC1

InChI Key InChIKey=ZYUPRHZEIDPWDA-VQJSHJPSSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 395644   

TargetProgrammed cell death 1 ligand 1 [19-238]/protein 1 [25-167](Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM395644((R)-1-((7-cyano- 2-(2,2'-dimethyl- 3'-(5-(2-(4- me...)
Affinity DataIC50: <10nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProgrammed cell death 1 ligand 1 [19-238]/protein 1 [25-167](Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM395644((R)-1-((7-cyano- 2-(2,2'-dimethyl- 3'-(5-(2-(4- me...)
Affinity DataIC50: <10nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProgrammed cell death 1 ligand 1 [19-238]/protein 1 [25-167](Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM395644((R)-1-((7-cyano- 2-(2,2'-dimethyl- 3'-(5-(2-(4- me...)
Affinity DataIC50:  3.00E+3nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent