BDBM395644 (R)-1-((7-cyano- 2-(2,2'-dimethyl- 3'-(5-(2-(4- methylpiperazin- 1-yl)acetyl)-5,6- dihydro-4H- pyrrolo[3,4-d]- oxazol-2-yl)-[1,1'- biphenyl]-3-yl)- benzo[d]oxazol- 5-yl)methyl)-3-::US10308644, Example 254::US10800768, Example 254::US11339149, Example 254
SMILES CN1CCN(CC(=O)N2Cc3nc(oc3C2)-c2cccc(c2C)-c2cccc(-c3nc4cc(CN5CC[C@](C)(C5)C(O)=O)cc(C#N)c4o3)c2C)CC1
InChI Key InChIKey=ZYUPRHZEIDPWDA-VQJSHJPSSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 395644
TargetProgrammed cell death 1 ligand 1 [19-238]/protein 1 [25-167](Homo sapiens (Human))
Incyte
US Patent
Incyte
US Patent
TargetProgrammed cell death 1 ligand 1 [19-238]/protein 1 [25-167](Homo sapiens (Human))
Incyte
US Patent
Incyte
US Patent
Affinity DataIC50: <10nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
TargetProgrammed cell death 1 ligand 1 [19-238]/protein 1 [25-167](Homo sapiens (Human))
Incyte
US Patent
Incyte
US Patent