BDBM395645 (3R)-1-((7-cyano- 2-(2,2'-dimethyl- 3'-(5-(2-(5-methyl- 2,5-diazabicyclo- [2.2.1]heptan-2- yl)acetyl)-5,6- dihydro-4H- pyrrolo[3,4-d]- oxazol-2-yl)- biphenyl-3-yl)- benzo[d]oxazol-::US10308644, Example 255::US10800768, Example 255::US11339149, Example 255

SMILES CN1CC2CC1CN2CC(=O)N1Cc2nc(oc2C1)-c1cccc(c1C)-c1cccc(-c2nc3cc(CN4CC[C@H](C4)C(O)=O)cc(C#N)c3o2)c1C

InChI Key InChIKey=AAYURXRQCHUFOV-CSJMBUEXSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 395645   

TargetProgrammed cell death 1 ligand 1 [19-238]/protein 1 [25-167](Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM395645((3R)-1-((7-cyano- 2-(2,2'-dimethyl- 3'-(5-(2-(5-me...)
Affinity DataIC50: <10nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProgrammed cell death 1 ligand 1 [19-238]/protein 1 [25-167](Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM395645((3R)-1-((7-cyano- 2-(2,2'-dimethyl- 3'-(5-(2-(5-me...)
Affinity DataIC50: <10nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProgrammed cell death 1 ligand 1 [19-238]/protein 1 [25-167](Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM395645((3R)-1-((7-cyano- 2-(2,2'-dimethyl- 3'-(5-(2-(5-me...)
Affinity DataIC50:  3.00E+3nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent