BDBM395646 (R)-1-((2-(2′-chloro-3′-(5-(2-((R)-3-hydroxypyrrolidin-1-yl)acetyl)-5,6-dihydro-4H-pyrrolo[3,4-d]oxazol-2-yl)-2-methyl-[1,1′-biphenyl]-3-yl)-7-cyanobenzo[d]oxazol-5-yl)methyl)pyrrolidine-3-carboxylic acid::US10308644, Example 256::US10800768, Example 256::US11339149, Example 256

SMILES Cc1c(cccc1-c1cccc(-c2nc3CN(Cc3o2)C(=O)CN2CC[C@@H](O)C2)c1Cl)-c1nc2cc(CN3CC[C@H](C3)C(O)=O)cc(C#N)c2o1

InChI Key InChIKey=ZEEWQBRKDGIJIN-ILBGXUMGSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 395646   

LigandPNGBDBM395646((R)-1-((2-(2′-chloro-3′-(5-(2-((R)-3-h...)
Affinity DataIC50: <10nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

LigandPNGBDBM395646((R)-1-((2-(2′-chloro-3′-(5-(2-((R)-3-h...)
Affinity DataIC50: <10nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

LigandPNGBDBM395646((R)-1-((2-(2′-chloro-3′-(5-(2-((R)-3-h...)
Affinity DataIC50:  3.00E+3nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent