BDBM395650 (R)-1-((7-cyano- 2-(3'-(1,5- dimethyl-4,5,6,7- tetrahydro-1H- imidazo[4,5-c]- pyridine-2- carboxamido)-2,2'- dimethylbiphenyl-::US10308644, Example 260::US10800768, Example 260::US11339149, Example 260

SMILES CN1CCc2c(C1)nc(C(=O)Nc1cccc(c1C)-c1cccc(-c3nc4cc(CN5CC[C@](C)(C5)C(O)=O)cc(C#N)c4o3)c1C)n2C

InChI Key InChIKey=UKCXTPGLTIWOLX-KXQOOQHDSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 395650   

TargetProgrammed cell death 1 ligand 1 [19-238]/protein 1 [25-167](Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM395650((R)-1-((7-cyano- 2-(3'-(1,5- dimethyl-4,5,6,7- tet...)
Affinity DataIC50: <10nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProgrammed cell death 1 ligand 1 [19-238]/protein 1 [25-167](Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM395650((R)-1-((7-cyano- 2-(3'-(1,5- dimethyl-4,5,6,7- tet...)
Affinity DataIC50: <10nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProgrammed cell death 1 ligand 1 [19-238]/protein 1 [25-167](Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM395650((R)-1-((7-cyano- 2-(3'-(1,5- dimethyl-4,5,6,7- tet...)
Affinity DataIC50:  3.00E+3nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent