BDBM395654 4-(2-(2-chloro- 3'-(7-cyano-5- (((R)-3-hydroxy- pyrrolidin-1-yl) methyl)benzo[d]- oxazol-2-yl)-2'- methylbiphenyl-3- ylcarbamoyl)-1- methyl-6,7-dihydro- 1H-imidazo[4,5-c]- pyridin-5(4H)-yl)-::US10308644, Example 264::US10800768, Example 264::US11339149, Example 264
SMILES Cc1c(cccc1-c1cccc(NC(=O)c2nc3CN(CCc3n2C)C2CCCC(CC2)C(O)=O)c1Cl)-c1nc2cc(CN3CC[C@@H](O)C3)cc(C#N)c2o1
InChI Key InChIKey=HIGLURAIZHIKMK-UYTNTSMZSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 395654
TargetProgrammed cell death 1 ligand 1 [19-238]/protein 1 [25-167](Homo sapiens (Human))
Incyte
US Patent
Incyte
US Patent
TargetProgrammed cell death 1 ligand 1 [19-238]/protein 1 [25-167](Homo sapiens (Human))
Incyte
US Patent
Incyte
US Patent
Affinity DataIC50: <10nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
TargetProgrammed cell death 1 ligand 1 [19-238]/protein 1 [25-167](Homo sapiens (Human))
Incyte
US Patent
Incyte
US Patent