BDBM395654 4-(2-(2-chloro- 3'-(7-cyano-5- (((R)-3-hydroxy- pyrrolidin-1-yl) methyl)benzo[d]- oxazol-2-yl)-2'- methylbiphenyl-3- ylcarbamoyl)-1- methyl-6,7-dihydro- 1H-imidazo[4,5-c]- pyridin-5(4H)-yl)-::US10308644, Example 264::US10800768, Example 264::US11339149, Example 264

SMILES Cc1c(cccc1-c1cccc(NC(=O)c2nc3CN(CCc3n2C)C2CCCC(CC2)C(O)=O)c1Cl)-c1nc2cc(CN3CC[C@@H](O)C3)cc(C#N)c2o1

InChI Key InChIKey=HIGLURAIZHIKMK-UYTNTSMZSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 395654   

TargetProgrammed cell death 1 ligand 1 [19-238]/protein 1 [25-167](Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM395654(4-(2-(2-chloro- 3'-(7-cyano-5- (((R)-3-hydroxy- py...)
Affinity DataIC50: <10nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProgrammed cell death 1 ligand 1 [19-238]/protein 1 [25-167](Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM395654(4-(2-(2-chloro- 3'-(7-cyano-5- (((R)-3-hydroxy- py...)
Affinity DataIC50: <10nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProgrammed cell death 1 ligand 1 [19-238]/protein 1 [25-167](Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM395654(4-(2-(2-chloro- 3'-(7-cyano-5- (((R)-3-hydroxy- py...)
Affinity DataIC50:  3.00E+3nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent