BDBM395966 US10308660, Example 42
SMILES Cn1c(nc(N)c(Sc2ccnc(N)c2Cl)c1=O)N1CCC2(CC(F)(F)C[C@H]2N)CC1
InChI Key InChIKey=OOZUDBICHRCGIM-LLVKDONJSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 395966
Affinity DataIC50: 14nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phosphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair