BDBM397327 US10596172, Compound I-132::US10828300, Compound I-132::US11351168, Compound I-132::US9987276, Compound I-132

SMILES COc1cccc(Nc2ncc(c(Nc3ccc4CN(Cc4c3)C(=O)C=C)n2)C(F)(F)F)c1

InChI Key InChIKey=XRMYEWRTHGYLGR-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 397327   

TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Celgene Car

US Patent
LigandPNGBDBM397327(US10596172, Compound I-132 | US10828300, Compound ...)
Affinity DataIC50: <10nMAssay Description:Briefly, 10× stocks of EGFR-WT (PV3872) from Invitrogen and EGFR-T790M/L858R (40350) from BPS Bioscience, San Diego, Calif., 1.13×ATP (AS001A) and ap...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent