BDBM39880 1-(ethylamino)-3-methyl-3H-naphtho[1,2,3-de]quinoline-2,7-dione::MLS000043530::SMR000020347::cid_712714

SMILES CCNc1c2-c3ccccc3C(=O)c3cccc(n(C)c1=O)c23

InChI Key InChIKey=AVFQMEROHOFTEF-UHFFFAOYSA-N

Data  7 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 39880   

Target14-3-3 protein gamma(Homo sapiens (Human))
Emory University

Curated by PubChem BioAssay
LigandPNGBDBM39880(1-(ethylamino)-3-methyl-3H-naphtho[1,2,3-de]quinol...)
Affinity DataIC50:  7.29E+3nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN MLSCN Grant: 1 X01MH78953-01 The 14-3-3 pr...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetEphrin type-B receptor 4(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM39880(1-(ethylamino)-3-methyl-3H-naphtho[1,2,3-de]quinol...)
Affinity DataIC50:  2.57E+4nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetPlectin(Homo sapiens (Human))
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM39880(1-(ethylamino)-3-methyl-3H-naphtho[1,2,3-de]quinol...)
Affinity DataIC50:  2.00E+5nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Nas Of Ukraine

Curated by ChEMBL
LigandPNGBDBM39880(1-(ethylamino)-3-methyl-3H-naphtho[1,2,3-de]quinol...)
Affinity DataIC50:  1.00E+4nMAssay Description:Competitive inhibition of human ASK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Salmonella enterica subsp. enterica serovar Choler...)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM39880(1-(ethylamino)-3-methyl-3H-naphtho[1,2,3-de]quinol...)
Affinity DataIC50:  3.65E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institute (TS...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetBeta-lactamase(Pseudomonas aeruginosa)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM39880(1-(ethylamino)-3-methyl-3H-naphtho[1,2,3-de]quinol...)
Affinity DataIC50:  8.01E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institute (TS...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetProtein LANA1(Human herpesvirus 8)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM39880(1-(ethylamino)-3-methyl-3H-naphtho[1,2,3-de]quinol...)
Affinity DataEC50:  571nMAssay Description:Primary Collaborators: Kenneth Kaye,Brigham & Womens,Boston MA,kkaye@rics.bwh.harvard.edu,617-525-4256 Chantal Beauchemin,Brigham & Womens,Boston MA,...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetBeta-lactamase(Pseudomonas aeruginosa)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM39880(1-(ethylamino)-3-methyl-3H-naphtho[1,2,3-de]quinol...)
Affinity DataIC50:  4.93E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institute (TS...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay