BDBM398803 1-((3S,4R)-4-(3,4- difluorophenyl)-1- (2-methoxyethyl) pyrrolidin-3-yl)-3- (3-methyl-4- (methylthio)-1- phenyl-1H-pyrazol- 5-yl)urea::US10323022, Example 280

SMILES COCCN1C[C@@H](NC(=O)Nc2c(SC)c(C)nn2-c2ccccc2)[C@@H](C1)c1ccc(F)c(F)c1

InChI Key InChIKey=VSNTUMAYLRHFFT-SIKLNZKXSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 398803   

TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM398803(1-((3S,4R)-4-(3,4- difluorophenyl)-1- (2-methoxyet...)
Affinity DataIC50: <100nMAssay Description:Trk enzymatic selectivity was assessed using Omnia Kinase Assay reagents from Invitrogen Corp. Enzyme (TrkA from Invitrogen Corp.) and test compound ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent