BDBM398815 5-(3-((3S,4R)-4-(4- fluorophenyl)-1-(2- methoxyethyl)pyrrolidin-3- yl)ureido)-N,4-dimethyl-1- phenyl-1H-pyrazole-3- carboxamide::US10323022, Example 292

SMILES CNC(=O)c1nn(c(NC(=O)N[C@@H]2CN(CCOC)C[C@H]2c2ccc(F)cc2)c1C)-c1ccccc1

InChI Key InChIKey=QEKOSROGXDLSHF-FCHUYYIVSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 398815   

TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM398815(5-(3-((3S,4R)-4-(4- fluorophenyl)-1-(2- methoxyeth...)
Affinity DataIC50: <100nMAssay Description:Trk enzymatic selectivity was assessed using Omnia Kinase Assay reagents from Invitrogen Corp. Enzyme (TrkA from Invitrogen Corp.) and test compound ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent