BDBM398827 1-(trans-4-(3-chloro-4- fluorophenyl)-1-(2- methoxyethyl)pyrrolidin-3-yl)- 3-(4-methyl-3-(1-methyl-2- oxo-1,2-dihydropyridin-4-yl)- 1-phenyl-1H-pyrazol-5-yl)urea::US10323022, Example 304

SMILES COCCN1C[C@@H](NC(=O)Nc2c(C)c(nn2-c2ccccc2)-c2ccn(C)c(=O)c2)C(C1)c1ccc(F)c(Cl)c1

InChI Key InChIKey=LUKORDKREXMQQE-ANWICMFUSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 398827   

TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM398827(1-(trans-4-(3-chloro-4- fluorophenyl)-1-(2- methox...)
Affinity DataIC50: <100nMAssay Description:Trk enzymatic selectivity was assessed using Omnia Kinase Assay reagents from Invitrogen Corp. Enzyme (TrkA from Invitrogen Corp.) and test compound ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent