BDBM398834 1-((3S,4R)-4-(3,4- difluorophenyl)-1-(2- methoxyethyl)pyrrolidin-3-yl)- 3-(4-ethyl-1'-methyl-1-phenyl- 1H,1'H-[3,4'-bipyrazol]-5- yl)urea::US10323022, Example 311

SMILES CCc1c(NC(=O)N[C@@H]2CN(CCOC)C[C@H]2c2ccc(F)c(F)c2)n(nc1-c1cnn(C)c1)-c1ccccc1

InChI Key InChIKey=GDZIGQAGGREXMW-JYFHCDHNSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 398834   

TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM398834(1-((3S,4R)-4-(3,4- difluorophenyl)-1-(2- methoxyet...)
Affinity DataIC50: <100nMAssay Description:Trk enzymatic selectivity was assessed using Omnia Kinase Assay reagents from Invitrogen Corp. Enzyme (TrkA from Invitrogen Corp.) and test compound ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent