BDBM399559 US10323036, Compound I-2::US10793574, Compound I-2::US11220508, Compound I-2
SMILES COCc1ccnc(Nc2cc(Nc3cccc(-c4nnn(C)n4)c3OC)c3c(n2)[nH]n(C)c3=O)c1
InChI Key InChIKey=RBFDIIIYNRFLOT-UHFFFAOYSA-N
Data 3 Kd
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 399559
TargetNon-receptor tyrosine-protein kinase TYK2 [V731I](Homo sapiens (Human))
Nimbus Lakshmi
US Patent
Nimbus Lakshmi
US Patent
Affinity DataKd: 0.300nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan® assay (Di...More data for this Ligand-Target Pair
TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Homo sapiens (Human))
Nimbus Lakshmi
US Patent
Nimbus Lakshmi
US Patent
Affinity DataKd: 0.300nMAssay Description:The binding reaction was assembled by combining 16 μl of DNA-tagged kinase extract, 3.8 μl liganded affinity beads, and 0.18 μl test c...More data for this Ligand-Target Pair
TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Homo sapiens (Human))
Nimbus Lakshmi
US Patent
Nimbus Lakshmi
US Patent
Affinity DataKd: 0.300nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan® assay (Di...More data for this Ligand-Target Pair