BDBM402341 6-(3-(2-chloro-4-((4- cyclopropyl-1-(2,6- dichlorophenyl)-1H-pyrazol- 5-yl)methoxy)phenyl)-3- hydroxyazetidin-1-yl)-5- fluoronicotinic acid::US10329286, Example 11::US11247986, Example 11
SMILES OC(=O)c1cnc(N2CC(O)(C2)c2ccc(OCc3c(cnn3-c3c(Cl)cccc3Cl)C3CC3)cc2Cl)c(F)c1
InChI Key InChIKey=YXBSANGYUBIGCK-UHFFFAOYSA-N
Data 2 EC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 402341
Affinity DataEC50: 3.80nMAssay Description:Expression and purification of the FXR-LBD: An overnight preculture of a transformed E. coli strain was diluted 1:20 in LB-Ampicillin medium and grow...More data for this Ligand-Target Pair
Affinity DataEC50: 3.80nMAssay Description:Determination of a ligand mediated Gal4 promoter driven transactivation to quantify ligand binding mediated activation of FXR was performed as follow...More data for this Ligand-Target Pair