BDBM402696 2-(azepan-3-ylamino)-N- [3-(difluoromethyl)-1- methyl-1H-pyrazol-4- yl]pyrrolo[2,1- f][1,2,4]triazine-7- carboxamide trifluoroacetate::US10329295, Example 19

SMILES Cn1cc(NC(=O)c2ccc3cnc(NC4CCCCNC4)nn23)c(n1)C(F)F

InChI Key InChIKey=MOEMZQSKNWPMLD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 402696   

TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM402696(2-(azepan-3-ylamino)-N- [3-(difluoromethyl)-1- met...)
Affinity DataIC50:  1nMAssay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent