BDBM402722 2-(2,5- diazabicyclo[2.2.2]oct-2- yl)-N-[3-(difluoromethyl)- 1-methyl-1H-pyrazol-4- yl]pyrrolo[2,1- f][1,2,4]triazine-7- carboxamide trifluoroacetate::US10329295, Example 29

SMILES Cn1cc(NC(=O)c2ccc3cnc(nn23)N2CC3CCC2CN3)c(n1)C(F)F

InChI Key InChIKey=YLTZCHYSAGYPRP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 402722   

TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM402722(2-(2,5- diazabicyclo[2.2.2]oct-2- yl)-N-[3-(difluo...)
Affinity DataIC50:  7nMAssay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent