BDBM402809 2-(3,8- diazabicyclo[3.2.1]oct-8- yl)-N-[3-(difluoromethyl)- 1-methyl-1H-pyrazol-4- yl]pyrrolo[2,1- f][1,2,4]triazine-7- carboxamide trifluoroacetate::US10329295, Example 121

SMILES Cn1cc(NC(=O)c2ccc3cnc(nn23)N2C3CCC2CNC3)c(n1)C(F)F

InChI Key InChIKey=MPXRZHSMLCKXKH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 402809   

TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM402809(2-(3,8- diazabicyclo[3.2.1]oct-8- yl)-N-[3-(difluo...)
Affinity DataIC50:  0.5nMAssay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent