BDBM402826 2-{[(1S,2R)- or (1R,2S)-2- amino-4,4- difluorocyclohexyl]amino}- N-[3-(difluoromethyl)-1- methyl-1H-pyrazol-4- yl]pyrrolo[2,1- f][1,2,4]triazine-7- carboxamide::US10329295, Example 139
SMILES Cn1cc(NC(=O)c2ccc3cnc(N[C@@H]4CCC(F)(F)C[C@@H]4N)nn23)c(n1)C(F)F
InChI Key InChIKey=IXIKUFKIBIPMML-WDEREUQCSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 402826
Affinity DataIC50: 3nMAssay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair