BDBM402836 2-[(3R,5R)-3-amino-5- fluoropiperidin-1-yl]-N-[1- methyl-3- (trifluoromethyl)-1H- pyrazol-4-yl]pyrrolo[2,1- f][1,2,4]triazine-7- carboxamide trifluoroacetate::US10329295, Example 149
SMILES Cn1cc(NC(=O)c2ccc3cnc(nn23)N2C[C@H](N)C[C@@H](F)C2)c(n1)C(F)(F)F
InChI Key InChIKey=SPFJXZLDVRYPFS-NXEZZACHSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 402836
Affinity DataIC50: 0.800nMAssay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair