BDBM402846 N-[3-(difluoromethyl)-1- methyl-1H-pyrazol-4-yl]- 2-{[(3R,5S)-5- fluoropiperidin-3- yl]amino}pyrrolo[2,1- f][1,2,4]triazine-7- carboxamide::US10329295, Example 159
SMILES Cn1cc(NC(=O)c2ccc3cnc(N[C@H]4CNC[C@@H](F)C4)nn23)c(n1)C(F)F
InChI Key InChIKey=LZXOEJFSPVTZEY-VHSXEESVSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 402846
Affinity DataIC50: 0.5nMAssay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair